My research interests focus on the construction of transgenic mouse model. CRISPR-Cas9 is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence. With this magical tool I try to edit some genes related to male fertility and knockout or knock-in these genes. These mouse models will be used to study the molecular mechanisms within spermatogonial stem cells that control self-renewal and differentiation.